BDBM18046 5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, 1::5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE::5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine::5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine, 2c::CHEMBL83547::GW578

SMILES Cc1ccc(Sc2cccc3nc(N)nc(N)c23)cc1

InChI Key InChIKey=UOJFGEAPSYQDIP-UHFFFAOYSA-N

Data  2 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18046   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Research Institute, Hospital For Sick Children

LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)
Affinity DataIC50:  7.80E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed